Endocrine Abstracts

Background: Early diagnosis and treatment of high blood pressure (BP) and high cholesterol is important to reduce cardiovascular mortality risk.Methods: We assessed actual BP and LDL-cholesterol (LDL-C) levels in 88,029 participants (36,122 men), aged 18-80 yrs, without diabetes, from the Dutch Lifelines Cohort study. Participants were categorized according to degree of obesity (normal weight, overweight, obese) and age decade group. BP measurement was r...

Aim: We assessed in both men and women within different BMI- and age classes the prevalence of MetS and its individual components, since these specific estimates obtained simultaneously in a large western European population are lacking. Secondly, we measured as well how age-specific blood pressure (BP) cut-offs affect the prevalence of elevated BP and MetS.Methods: Data of 74 531 western European participants, aged 18–79 years, were obtained from t...

Introduction: The metabolic syndrome (MetS) is a strong predictor of cardiovascular risk. It is influenced by environmental factors, and its prevalence is high in subjects with obesity.Design: We assessed differences in glucose- and lipid parameters, and hsCRP and microalbuminuria (MA) in obese subjects with and without metabolic syndrome (MetS) in LifeLines, a population-based study. Included were subjects 18–80 years, with BMI>30 kg/m2</s...

Introduction: Obesity is increasingly prevalent in Western society. In addition to medical consequences, obesity also affects health-related quality of life (HR-QOL).Design: We assessed the differences in HR-QOL in obese participants with and without metabolic syndrome (MetS), by level of obesity and level of inflammation, in the LifeLines Cohort study, a population-based study. In total, 12 765 subjects age 18–80 years, with BMI >30 kg/m2<...

Background: The clustering of metabolic and cardiovascular risk factors is known as the metabolic syndrome (MetS). Lifestyle factors like smoking may contribute to the differences in prevalence of the MetS. The aim of this study was to examine the association between smoking and the MetS and its components in different BMI classes.Methods: The present cross-sectional evaluation comprised 24 762 men and 35 558 women, participating in the LifeLines Cohort ...